General Western Blot Reagents
Abcam DAF-FM DA, Nitric o x ide quantification reagent, 5MG
MW 496.42 g/mol, Purity >98%. Cell permeable reagent for quantification of low concentrations of nitric oxide in solution. Essentially nonfluorescent until it is hydrolyzed to DAF-FM (ab145297) by intracellular esterases and reacts with NO to form a fluorescent benzotriazole.
The product is subject to the following: Abcam Restricted Use Statement
Abcam N-Methyl-4-phenylpyridinium Iodide (MPP+), Dopaminergic selective neuroto x in, 250MG
MW 297.13 Da, Purity >98%. Dopaminergic selective neurotoxin. Active MPTP metabolite. Interferes with oxidative phosphorylation and induces mitochondrial dysfunction. Deplete cellular ATP. Shows Parkinson effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam 4-Hydro x ynonenal, Lipid pero x idation marker, 1MG
MW 156.22 Da, Purity >97%. Marker of lipid peroxidation. Prevents NF-κB activation and TNF expression by inhibiting IκB phosphorylation. Range of biological effects such as cytotoxicity, growth inhibiting activity, genotoxicity, and chemotactic activity. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (Z)-4-Hydro x ytamo x ifen, estrogen receptor modulator, 5MG
MW 387.5 Da, Purity >98%. Potent and selective estrogen receptor antagonist (IC₅₀ = 7 nM). Active metabolite of (Z)-tamoxifen (ab120656) and exhibits higher potency in vitro. Shows antiproliferative effect (IC₅₀ = 27 μM). Induces p21 nuclear localization.
The product is subject to the following: Abcam Restricted Use Statement
Abcam (Z)-4-Hydro x ytamo x ifen, estrogen receptor modulator, 25MG
MW 387.5 Da, Purity >98%. Potent and selective estrogen receptor antagonist (IC₅₀ = 7 nM). Active metabolite of (Z)-tamoxifen (ab120656) and exhibits higher potency in vitro. Shows antiproliferative effect (IC₅₀ = 27 μM). Induces p21 nuclear localization.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Phosphatase Inhibitor Cocktail III, 1ML
Phosphatase Inhibitor Cocktail III (ab201114) is part of the multiplex kits range. Abcam offers high-quality biological reagents and tools including antibodies, proteins, assays, cell lines and lysates.
The product is subject to the following: Abcam Restricted Use Statement
Hach Company Filter, Membrane, Pore Size 0.45 µm, Diameter 47 mm, 1000/pk, without pad
These 47-mm diameter, 0.45-µm pore size GN-Metricel membrane filters meet or surpass all U.S. Environmental Protection Agency (USEPA) and American Society for Testing and Materials (ASTM) specifications to ensure complete retention and maximum recovery of bacteria. Black membranes for yeast and mold are also available. Black membranes make yeast and mold colonies more distinct and easier to count. Filters are available in convenient, presterilized, individually sealed packs (P/N 13530-01 and 24903-00) or in resealable envelopes with 10 filters and 10 absorbent pads each (P/N 21269-00). Phosphate free.
Abcam ML-9, protein kinase inhibitor, 50MG
MW 361.3 Da, Purity >98%. Broad spectrum ATP-competitive protein kinase inhibitor (Ki values are 32, 4, and 54 μM for PKA, MLCK, and PKC respectively). Ca²+ channel blocker. Shows vasorelaxant effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam MMP-9 inhibitor, 500UG
MW 511.6 Da, Purity >95%. MMP-9 inhibitor. Role in tumor cell migration, invasion and angiogenesis. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Agomelatine, MT1/MT2 agonist and 5-HT2C antagonist, 100MG
MW 243.3 Da, Purity >99%. Potent MT1/MT2 agonist (Ki values are 0.1 and 0.12 nM, respectively). 5-HT2C antagonist (IC50 = 270 nM). Shows antidepressant effects *in vivo*. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Agomelatine, MT1/MT2 agonist and 5-HT2C antagonist, 500MG
MW 243.3 Da, Purity >99%. Potent MT1/MT2 agonist (Ki values are 0.1 and 0.12 nM, respectively). 5-HT2C antagonist (IC50 = 270 nM). Shows antidepressant effects *in vivo*. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam D-erythro-Dihydrosphingosine-1-phosphate, sphingosine 1-phosphate receptor ligand, 1MG
MW 381.5 Da, Purity >98%. Sphingosine 1-phosphate (S1P) receptor ligand (Ki = 15 nM). May be used as negative control for intracellular effects of S1P (ab141748). Anti-fibrotic effect in fibroblasts.
The product is subject to the following: Abcam Restricted Use Statement
ProteinSimple 12-230 KDA WES SEPARATION MODU
12-230 kDa Wes Separation Module, 2 x 25 capillary cartridges.Use with a Detection Module. Reagents for 50 data points includes two parts: Separation box with 2x Capillary Cartridges (25 capillaries per cartridge), 2x Wes 12-230 kDa pre-filled Plates (pre-filled with Separation Matrix 2, Stacking Matrix 2, Split Running Buffer 2 and Matrix Removal Buffer), Sample Buffer, Wash Buffer (Store at RT), plus 1x Standard Pack 1 clamshell with 2x DTT and 2x FL master mix with 29 kDa System Control protein. (Store at 4 C).
Rockland Immunochemicals Mouse TrueBlot Set (with IP Agarose beads) - 88-7788-31
Mouse IgG TrueBlot ULTRA is provided as 1000X solution. We recommend incubating the blots from minigels in sealed bags with minimal volume (2-3 mLs). If used conservatively at 2.5mls/blot will yield enough reagent for 20 blots. Note that there are three key procedural considerations: 1. Protein A or G beads may be used with the mouse, goat and sheep TrueBlot secondaries, but not with the rabbit TrueBlot secondary. Use of protein A or G beads with the rabbit TrueBlot will result in contaminating bands. 2. Immunoprecipitate should be completely reduced. 3. BLOTTO/Milk should be used as the blocking protein for the immunoblot. We recommend using a large bore pipet to pipet up the liquid for use. To achieve best results when detecting mouse IgG1 subtypes, we recommend performing a dot blot or titration to determine the optimal dilution. Specific conditions for each protein and antibody combination should be specifically optimized by the end user.
Genhunter Corporation PerfectWestern, 3-Sectional-Strip, Black
PerfectWestern, 3-Sectional-Strip, Black (Qty. 1-4)